The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
BBSRC: One Health Approaches to Accelerate Vaccine Development, Oct 2017
Closing date: 25 Oct 2017 16:00 BST
BBSRC, on behalf of the Department of Health and the UK Vaccine Network, is pleased to announce a £5 million call for ‘One Health Approaches to Accelerate Vaccine Development’.
The call aims to support comparative ‘One Health’ research which will promote antigen discovery, enhance understanding of disease pathogenesis, and accelerate vaccine development for a range of viral and bacterial families that are known to have a significant impact on animal and human health in low and/or middle income countries.
This call forms part of the UK government’s commitment to Official Development Assistance (ODA), therefore research projects must address challenges primarily relevant to the health or prosperity of low and/or middle income countries on the Organisation for Economic Co-operation and Development (OECD) DAC List.
This call will support research that takes a comparative ‘One Health’ approach to enhance vaccine development focusing on viruses and bacteria that have outbreak epidemic potential. Research on the following viral and bacterial families is particularly encouraged: Arenaviridae, bunyaviridae, coronaviridae, filoviridae, flaviviridae, paramyxoviridae, togoviridae, enterobacteriales and coxiallaceae but research on other bacterial or viral families will be considered where a case can be made that there is significant outbreak epidemic potential.
Areas of possible focus include:
Antigen discovery, antigenic variability
Host pathogen interactions
Immune correlates of protection - naturally acquired immunity.
It is envisaged that research will focus on one or more related bacterial or viral pathogens of veterinary and medical importance in countries on the OECD DAC list. However, research on zoonotic bacterial or viral pathogens is also welcomed.
For the full call text please visit the Academy of Medical Sciences' grant call webpage.