University of Pavia, Italy
Structural vaccinology, antigen design, epitope design, diagnostics
My research aims to:
1) to integrate molecular dynamics, computational physical-chemistry and bioinformatics approaches to study the dynamics and specificity of protein-ligand recognition and binding
2) to translate this information into the rational design of new molecules taking the full flexibility of the receptor and the ligand into account
3) to develop computational methods to understand the determinants of protein-antibody and protein-protein interactions with the aim to design novel immunoreactive molecules.