Postdoctoral Research Fellow
TB, Shigellosis, Mycobacterium tuberculosis, Shigella flexneri, Shigella sonnei, animal models, zebrafish, trained innate immunity, innate immune vaccines
I am currently a Senior Research Fellow at the London School of Hygiene and Tropical Medicine. My research is focused on Infectious diseases. We use the zebrafish model to recapitulate human infections with a variety of bacteria, including Shigella, Salmonella, Mycobacterium and Staphylococcus. I am also interested in cell biology and we explore infections as a tool to obtain a better understanding of cell functions in both physiological and pathological contexts. Over the last few years, I focused on septins (a poorly understood component of the cytoskeleton) as well as on chemokines and chemokine receptors (important families of proteins which orchestrate crucial aspects of the host-immune response and inflammation). I also focus on the development of innovative strategies to counteract Shigella infections and we aim to identify new targets for vaccines or alternative treatments (i.e. innate vaccines, innate immune training & reprogramming). I previously carried out a Marie Curie-funded post-doctoral training at the Imperial College London and a Marie Curie-funded Ph.D. in the FishForPharma network, at Leiden University, where I was awarded a Ph.D. in Immunology and Microbiology, defending a thesis entitled "Exploitation of host chemokine signalling by pathogenic Mycobacteria". I obtained a M.Sc. in Molecular and Cellular Biology and a B.Sc. in Molecular and Computational Biology from Salerno University.
Profile page at LSHTM
Available on ORCID