Narisara Chantratita

Narisara Chantratita

Associate Professor

Mahidol University, Thailand

Tel: +66 819099772

Email: Narisara@tropmedres.ac ; Narisara.cha@mahidol.ac.th

 

 

 

VALIDATE Role:

Network Management Board member, Network Investigator

 

Research Keywords: 

Melioidosis, host-pathogen interaction

 

Biography:

I am an Associate Professor at Mahidol University. I have studied the interactions between the pathogen and human host in melioidosis for over twenty years, combining laboratory investigation with clinical studies. Based in the Department of Microbiology and Immunology, Faculty of Tropical Medicine at Mahidol University in Bangkok. I have conducted or been involved in numerous studies relating to melioidosis and other bacterial infections in northeast Thailand. For example, my Wellcome Trust Intermediate Fel­lowship Project, “Association between genetic polymor­phisms, innate immune responses and outcomes from sepsis in Thai patients with melioidosis and S. aureus infection” involved recruitment of hospitalized patients at four clinical sites in northeast Thailand: Ubon Rachathani, Udon Thani, Khon Kaen and Srinagarind Hospitals. I have worked since 2006 on studies of host genetic susceptibility, human inflammatory responses and laboratory diagnosis. I have developed a substantial repertoire of expertise in immunology, bacteriology, molecu­lar diagnostics, and bacterial and host genetics pertaining to melioidosis. I am currently a principal investigator of NIH/NIAID grant for the project “Determinants of outcomes and reinfection in melioidosis”. This project involved recruitment of melioidosis patients at nine study sites in northeast Thailand.

 

Related Websites: 

Profile page at Mahidol University

 

Key Publications:

Chantratita N, Tandhavanant S, Seal S, Wikraiphat C, Wongsuvan G, Ariyaprasert P, Suntornsut P, Teerawattanasook N, Jutrakul Y, Srisurat N, Chaimanee P, Mahavanakul W, Srisamang P, Phiphitaporn S, Mokchai M, Anukunananchai J, Wongratanacheewin S, Chetchotisakd P, Emond MJ, Peacock SJ, West TE. TLR4 genetic variation is associated with inflammatory responses in Gram-positive sepsis. Clin Microbiol Infect 2017; 23(1):47.e1-47.e10.

West TE, Wikraiphat C,Tandhavanant S, Ariyaprasert P, Suntornsut P, Okamoto S, Mahavanakul W, Srisamang P, Phiphitaporn S, Anukunananchai J, Chetchotisakd P, Peacock SJ, Chantratita N.  Patient characteristics, management and predictors of outcome from severe community-onset staphylococcal sepsis in northeast Thailand: a prospective multi-center study. Am J Trop Med Hyg 2017: 96(5):1042-49.

Chantratita N, Wikraiphat C, Tandhavanant S, Wongsuvan G, Ariyaprasert P, Suntornsut P,  Thaipadungpanit J, Teerawattanasook N, Jutrakul Y, Srisurat N, Chaimanee P, Anukunananchai J, Phiphitaporn S,  Srisamang P, Chetchotisakd P, West TE, Peacock SJ. Comparison of community-onset Staphylococcus aureus sepsis in Thailand: a prospective multicenter observational study. Clin Microbiol Infect 2016; 22(5):458.e11-9.

Wikraiphat C, Saiprom N, Tandhavanant S, Heiss C, Azadic P, Wongsuvan G, Tuanyok A, Holden MT, Burtnick MN, Brett PJ, Peacock SJ, Chantratita N. Colony morphology variation of Burkholderia pseudomallei is associated with antigenic variation and O-polysaccharide modification. Infect Immun 2015; 83(5): 2127-38. 

Chantratita N, Tandhavanant S, Myers ND, Chierakul W, Wuthiekanun V, Mahavanakul W, Limmathurotsakul D, Peacock SJ, West TE. Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand. Plos One 2014; 9(1):e83285.

Chantratita N, Tandhavanant S, Myers ND, Chierakul W, Robertson JD, Mahavanakul W, Singhasivanon P, Peacock SJ, West TE. Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis. Gene Immun 2014;15(2): 63-71.