The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
Project Manager in Melioidosis Vaccine Development
Deadline 14 December 2020
Nuffield Department of Medicine, Oxford, UK
Nuffield Department of Medicine (NDM), Centre for Tropical Medicine and Global Health is seeking to appoint a Project Manager to coordinate the melioidosis vaccine trial project. This is an exciting opportunity to join the University’s world-leading Medical Sciences department.
Melioidosis is a neglected tropical disease with a high mortality burden in low and middle income countries. We will undertake in Oxford the world’s first clinical trial of a vaccine candidate, in collaboration with scientists at the University of Nevada, USA. The Project Manager will be responsible for co-ordinating the development of the novel vaccine through the process of producing the vaccine in accordance with Good Manufacturing Practice (GMP) prior to initiating the clinical trial. Your main responsibility will be providing management support to this project led by Professor Dunachie at the Peter Medawar Building for Pathogen Research, with regulatory oversight from Alison Lawrie at The Jenner Institute. This will be a key role within the group ensuring successful completion of our research programme. The post holder will specifically manage the UK regulatory side of the manufacture of the new melioidosis vaccine candidate through the GMP process and obtaining MHRA approval. You will have the lead day-to-day responsibility for the successful execution of the project on-time and on-budget, supported by Professor Dunachie, Alison Lawrie and other team members and scientists. Additionally, you will be responsible for managing interactions between the various internal team members (preclinical and clinical), a number of external private-sector contractors and collaborators and the funders.
It is essential that you have a science degree, ideally in Medical or Life Sciences or any other relevant subjects. You will have demonstrable experience of leadership of large and complex projects and have strong skills in management of budgets and financial reporting. You will be highly organised with the ability to manage a vast amount of relatively complex information and have excellent verbal and written communication skills. Experience in GMP manufacture and the regulatory affairs are desirable, however additional support with training with be given where necessary to meet the needs of the role and support onward career progression.
Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.
This position is offered full time on a fixed term contract for 12 months in the first instance, however we would consider a suitable qualified candidate who wishes to work 4 days per week. This position is funded by the Medical Research Council (MRC) DPFS Award and Defence Threat Reduction Agency (DTRA).