The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
Postdoctoral Positions in Virology and Immunology
No stated deadline.
Cleveland Clinic, OH, United States
Dr. Michaela Gack’s laboratory at the Florida Research and Innovation Center of Cleveland Clinic, Port Saint Lucie, Florida, is seeking highly motivated postdoctoral fellows with a background in immunology, virology or closely related fields to be part of a team working to understand the interplay of viral pathogens with the human immune response.
Our group is interested in dynamic virus-host interactions, focusing on understanding the innate immune mechanisms of viral disease pathogenesis. Using cutting-edge gene-targeting screens combined with molecular, biochemical and cell biological approaches, we are identifying and characterizing the regulatory mechanisms that govern the detection of viruses through innate immune sensors, and the subsequent induction of signaling cascades leading to antiviral gene expression. Moreover, our group is interested in identifying novel host restriction factors of virus infection. Another major area of our research focuses on the mechanisms by which viruses antagonize the human antiviral immune response, and on the understanding of their roles in the viral life cycle. The Gack lab is also conducting translational research to discover novel broad-spectrum antiviral molecular targets.
The Cleveland ClinicFlorida Research and Innovation Center (CC-FRIC) is dedicated to the discovery and advancement of innovative translational research focused on infectious diseases and immuno-oncology. The Center is an exceptional state-of-the-art facility and has Shared Resource Flow Cytometry, Imaging, Bioinformatics, and BSL-3/ABSL-3 facilities https://www.lerner.ccf.org/fric/. The CC-FRIC is part of the recently established Global Center for Pathogen Research & Human Healthof Cleveland Clinichttps://www.lerner.ccf.org/pathogen-research/