The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
Zoonotic NTDs & One Health: Research needs & control strategies
Online, 5 Nov 2020 09:00 AM in Eastern Time (14:00 UCT)
This webinar will discuss how emotions can impact our health decision making and how they can fundamentally influence global health
About this Event
This session seeks to raise awareness of the impact the zoonotic pathogens and reservoir hosts may have on NTD control and elimination programmes and will discuss how programmes and policies can adapt adopt a One Health approach to NTD control. Understanding the complex population biology and transmission dynamics of multi-host parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most neglected of all the Neglected Tropical Diseases (NTDs). Transmission within and between animal reservoirs and humans can have important ecological and evolutionary consequences, driving the evolution and establishment of drug resistance, as well as providing selective pressures for spill-over, host switching, hybridisations and introgressions between animal and human parasites. Indeed, as climate change, population growth, and increasing urbanisation bring humans into ever greater contact with animals, zoonotic spillover episodes may be predicted to increase in frequency. The 2020 SARS-CoV-2 pandemic has illustrated the impact of shared infectious disease. Here we consider, with a focus primarily, but not exclusively, on zoonotic helminthic diseases, how multi-host, and often multi-parasite, transmission dynamics may affect the success of disease control programmes, particularly those neglected diseases of the developing world where the revised 2030 goals aim towards either elimination as a public health problem and/or ultimately interruption of transmission. We consider the different types of zoonotic interactions that occur, their potential relevance for current human control activities, and make suggestions for the development of an empirical evidence base and theoretical framework to better understand and predict the outcome of such interactions. In particular, we consider whether preventive chemotherapy can be successful without a One Health approach.