Mark Shiburah

Mark Shiburah

Research Scientist

Council for Scientific and Industrial Research (CSIR), Ghana

Email: markewusishiburah@gmail.com

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

Leishmania - Basic Science Research

 

Biography:

I am a Research Scientist at the Council for Scientific and Industrial Research (CSIR)-Animal Research Institute, specializing in genome editing and gene function studies. I hold a PhD in Genetics from the Sao Paulo State University, Brazil. I have 5 peer-reviewed publications, 2 book chapters and several peer-reviewed conference abstracts.

I have been with the CSIR-Animal Research Institute, since 2019 engaged with research in diverse fields. Currently, my focus is on infectious disease and vaccine research. My immediate goals include understanding the genetic basis of resistance and susceptibility to tick and tick-borne diseases in cattle, designing and developing multi-epitope vaccines against zika and dengue, and production of malaria vaccines, all of these projects aim to develop innovative solutions for disease prevention and control in both animals and humans.

 

Key Publications:

Research Papers and Preprints

  • Mark Ewusi Shiburah, Beatriz Cristina Dias de Oliveira, Habtye Bisetegn, et al., Ablation of telomerase reverse transcriptase in Leishmania major results in a senescent-like phenotype and loss of infectivity. bioRxiv 2023.11.10.566596; doi: https://doi.org/10.1101/2023.11.10.566596
  • Beatriz Cristina Dias de Oliveira, Mark Ewusi Shiburah, Luiz Henrique de Castro Assis, et al., The impact of knocking out the Leishmania major telomerase RNA (LeishTER): from altered cell proliferation to decreased parasite infectivity. Int. Journal of Biol Mac. https://doi.org/10.1016/j.ijbiomac.2024.135150
  • Assis, L.H.C.; Andrade-Silva, D.; Shiburah, M.E.; de Oliveira, B.C.D.; Paiva, S.C et al. Cell Cycle, Telomeres, and Telomerase in Leishmania spp.: What Do We Know So Far? Cells 2021, 10, 3195. https://doi.org/10.3390/cells10113195
  • de Oliveira BCD, Shiburah ME, Paiva SC, Vieira MR, Morea EGO, et al., Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania amazonensis Developmental Cycle and Population Proliferation. Front. Cell Dev. Biol. 9:713415. doi: 10.3389/fcell.2021.713415
  • Godson Aryee, Gabriel Adu-Aboagye, Mark Ewusi Shiburah, Theresah Nkrumah, David Amedorme. Correlation Between Egg Weight and Egg Characteristics in Japanese Quail, Animal and Veterinary Sciences. Volume 8, Issue 3, May 2020 , pp. 51-54. doi: 10.11648/j.avs.20200803.11
  • Hamidu J A, Adomako K, Adamu S, Ajaottor A M, Amankwah G J, Gyasi K M, Shiburah E M, Darko J O and Konadu L A 2018: Impact of layer egg storage conditions on eggs and embryo quality indices prior to incubation. Livestock Research for Rural Development. Volume 30, Article #184. http://www.lrrd.org/lrrd30/11/jaham30184.html 

 

Book chapters and Protocols

  • Beatriz C. D. de Oliveira, Luiz H. C. Assis, Mark E. Shiburah, Stephany C. Paiva, Veronica S. Fontes, Leilane S. de Oliveira Vitor L. da Silva & Marcelo S. da Silva& Maria Isabel N. Cano. Synchronization of Leishmania amazonensis cell cycle using hydroxyurea. Springer Nature (2022) doi https://doi.org/10.1007/978-1-0716-2736-5_10
  • Florencia Barbé-Tuana, Lucas Kich Grun, Vinícius Pierdoná, Beatriz Cristina Dias de Oliveira, Stephany Cacete Paiva, Mark Ewusi Shiburah, et al., Human Chromosome Telomeres. Springer Nature (2021). doi https://doi.org/10.1007/978-3-030-73151-9_7