Dr Chris Sundling
VALIDATE Role: Investigator
Research Keywords: TB, malaria, HIV, B cells, antibodies, adaptive immunity
Biography: Our research focuses on understanding the interplay between different infectious diseases and the immune system. In order to study the immune response after infection we use state-of-the-art technology to investigate the immune system on a cellular, molecular, and genetic level. We then use bioinformatics to analyse the high-dimensional data and combine the results with clinical variables. By comparing several diseases, we can identify unique features associated with the individual pathogens, which in turn can be useful for developing novel diagnostic tests or pin-point potential targets for therapeutics. We also achieve an improved understanding of how the immune system responds to a given infection on a systems scale, which we then further investigate mechanistically.