Mariateresa Coppola
PhD Student Leiden University Research Center, Netherlands Email: m.coppola@lumc.nl
VALIDATE Role: Network Affiliate
Research Keywords: TB, vaccine, immunology Biography: Since 2013 I have been working on the discovery of novel Mycobacterium tuberculosis antigens by using genomics, in-silico tools and high-throughput sequencing technologies and on studying the antigenicity of such proteins by comprehensive comparison of pathogen-specific immunity in health and disease. Besides, I have been trained for 3 years as vaccinologist in the European Network Vactrain.
Related Websites: Profile on Vactrain
Key Publications: Genome wide approaches discover novel Mycobacterium tuberculosis antigens as correlates of infection, disease, immunity and targets for vaccination. Semin Immun. 2018 Vaccines for Leprosy and Tuberculosis: Opportunities for Shared Research, Development and Application. Front Immunol. 2018 TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. Front Immunol. 2017 Differences in IgG responses against infection phase related Mycobacterium tuberculosis (Mtb) specific antigens in individuals exposed or not to Mtb correlate with control of TB infection and progression. Tuberculosis (Edinb). 2017 New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles. Sci Rep. 2016 Synthetic Long Peptide Derived from Mycobacterium tuberculosis Latency Antigen Rv1733c Protects against Tuberculosis. Clin Vaccine Immunol. 2015 Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method. PLoS One. 2014 Multi-functional flow cytometry analysis of CD4+ T cells as an immune biomarker for latent tuberculosis status in patients treated with tumour necrosis factor (TNF) antagonists. Clin Exp Immunol. 2014 Use of a contact center telephone helpline in rheumatology outpatient management: a five-year experience analysis and patients' perception. Mod Rheumatol. 2014 Mycobacterial Interferon-γ Release Variations During Longterm Treatment with Tumor Necrosis Factor Blockers: Lack of Correlation with Clinical Outcome. J Rheumatol 2012 |
