Zimvo Obasa
Post-Doctoral Research Fellow Stellenbosch University Tel: +27840954190 Email: maqeda@sun.ac.za
VALIDATE Role: Network Associate
Research Keywords: TB, Animal Models, Macrophage Models, Persisters, Nanotechnology and Vaccination
Biography: Dr. Zimvo Obasa is a postdoctoral researcher at Stellenbosch University, specializing in Molecular Biology. She holds a BSc degree in Human Life Sciences (2014), an MSc in Human Physiology (2017), and a PhD in Molecular Biology (2021). During her doctoral studies, Dr. Obasa focused on elucidating host immune responses triggered by Mycobacterium tuberculosis persisters in macrophage cultures. She also developed and validated a trackable murine model for studying Mycobacterium persister formation in Balb/c mice. Currently, her postdoctoral research is centered on evaluating the in vivo response to and efficacy of novel nanoparticle (NP) formulations as a host-directed therapy for eradicating all forms of Mycobacterium tuberculosis in C3HeB/FeJ (Kramink) mice. By utilizing the Kramnik mouse strain, Dr. Obasa aims to assess the impact of NPs on immuno-pathology and vice versa. Her work holds promise in contributing to the advancement of tuberculosis control strategies, particularly in developing more effective drug treatment regimens.
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